Domestic Minor Sex Trafficking Deterrence and Victims Support Act of 2010

Domestic Minor Sex Trafficking Deterrence and Victims Support Act of 2010 - Expresses the sense of Congress that: (1) the Attorney General should implement changes to the National Crime Information Center (NCIC) to identify endangered juveniles; (2) funds awarded under the Edward Byrne Memorial Justice Assistance Grant Program should be used to provide education, training, deterrence, and prevention programs relating to sex trafficking of minors; (3) states should treat minor victims of sex trafficking as crime victims rather than as criminal defendants or juvenile delinquents and adopt and amend laws to protect and provide compensation to such victims; and (4) demand for commercial sex with sex trafficking victims must be deterred through consistent law enforcement.

Authorizes the Assistant Attorney General for the Office of Justice Programs to award one-year block grants to up to six state or local governments in different regions of the United States that have significant sex trafficking to combat such trafficking. Requires grant funds to be used to provide shelter and services to minor victims of sex trafficking and for training for service providers.

Amends title IV of the Social Security Act (Grants to States for Needy Families with Children and for Child-Welfare Services) to require states to adopt procedures for reporting information on missing or abducted children for entry into the NCIC database.

Amends the Crime Control Act of 1990 to require: (1) the Attorney General's annual statistical summary under such Act to include the total number of missing child reports received and the total number of entries made to the NCIC database; and (2) state law enforcement agencies to update the record of a missing child with a photograph taken within the previous 180 days and to notify the National Center for Missing and Exploited Children of each report of a child missing from a foster care family home or childcare institution.