Working and Reacting (WAR) Against Meth Act of 2000

(Sec. 4) Modifies CSA provisions regarding endangering human life while illegally manufacturing a controlled substance to: (1) set penalties for harm to the environment, if the controlled substance consists of methamphetamine; (2) provide for imprisonment for up to 40 years, as well as a possible fine, for violations; and (3) make any penalty under provisions regarding the establishment of controlled substance manufacturing operations in addition to any penalty under such provisions regarding harm to human life or to the environment.

Specifies that in any case where the conduct at issue is, relates to, or involves the manufacture of amphetamine or methamphetamine, such conduct shall, by itself, be rebuttably presumed to constitute the creation of a substantial risk of harm to human life or to the environment.

(Sec. 5) Provides that the El Paso Intelligence Center (EPIC) and the Los Angeles County Regional Criminal Information Clearinghouse (LA Clearinghouse), at the direction of the Attorney General, shall jointly and in concert constitute the National Center for Methamphetamine Clandestine Laboratory Information. Requires: (1) EPIC's National Clandestine Laboratory Seizure Intelligence database to provide for the nationwide electronic reporting, capture, and retrieval of clandestine laboratory seizure information; and (2) such information to be analyzed by the LA Clearinghouse, in concert and coordination with EPIC, and disseminated to appropriate law enforcement agencies in a timely manner. Authorizes appropriations.