Children's Lead SAFE Act

Requires each contract between the State and an entity responsible for provision of medical assistance under the State plan to provide for: (1) compliance with mandatory blood lead screening requirements consistent with prevailing guidelines of the Centers for Disease Control and Prevention (CDC) for such screening; and (2) coverage of qualified lead treatment services. Allows reimbursement for qualified lead treatment services for children with elevated blood lead levels. Provides for enhanced Federal matching contributions for an information retrieval system that determines whether a child is enrolled under a State plan and whether an enrolled child has received mandatory early and periodic screening, diagnostic, and treatment services.

Amends the Child Nutrition Act of 1966 and the Head Start Act to mandate blood lead poisoning screening tests for an infant or child to be eligible to participate in either the special supplemental food program for women, infants, and children (WIC) or early Head Start and Head Start programs.

Amends SSA title XXI (Children's Health Insurance Program) (CHIP) to mandate CHIP coverage for blood lead poisoning screening tests for children Amends the Public Health Service Act and SSA title V (Maternal and Child Health Services) with regard to grants for lead poisoning related activities. Authorizes appropriations.

Imposes specified requirements on the CDC Director, including that the Director offer various assistance to the States with regard to children and lead poisoning. Authorizes appropriations.

Outlines provisions for training and congressional reports with regard to HHS' Health Resources and Services Administration and childhood lead poisoning and blood lead screening tests.

Mandates a CDC bonus program to improve the blood lead screening rates of States for children under age three enrolled in Medicaid. Details program particulars. Authorizes appropriations.